This summer, a team from Washington State University, led by Carrie Cuttler, an associate professor of psychology, with colleagues at UCLA published the results of a human trial on the effects of 20mg of hemp-derived CBG.
This double-blind placebo trial was the first of its kind to test the results of Cannabigerol (CBG) on mental wellbeing. The results, as they say, speak for themselves.
As they stated in the paper (emphasis ours):
Most notably, there was a significant main effect of CBG on subjective state ratings of anxiety. Specifically, there was a mean decrease in anxiety ratings of 0.95 on a 10-point scale which represents a 26.5% reduction in the already low levels of baseline anxiety (M = 3.59 on a 0–10 VAS) in the CBG condition. In contrast there was a 0.66-point reduction in anxiety ratings in the placebo condition (which represents a 22.5% reduction in anxiety in the placebo condition). These findings are in line with our survey findings wherein 51% of CBG users reported using CBG to manage anxiety and 78% claimed it was more effective than conventional anxiety medication.
Besides testing to see what positive effects CBG has for reducing anxiety, the team also tested to see how CBG compares to THC in terms of detrimental effects. They noted:
One of the most robust detrimental effects of THC is on verbal memory which guided our decision to include a test of verbal memory in the present study. We hypothesized that CBG would not impair memory, but our finding that CBG significantly enhanced verbal memory was unexpected.
They also tested (through survey and intoxication-measuring tools) for any impairing
Consistent with the lack of impairment detected in the CBG condition, participants reported no intoxicating effects of CBG. The overall mean intoxication rating (combined across the three time points) was less than 1 on a 0–10 VAS in both the CBG and placebo conditions. Similarly, overall mean ratings of subjective drug effects were low in both conditions and drug liking effects were neutral in both conditions at all timepoints suggesting a low potential for abuse.
As more and more science comes out, proving what has already been known by individuals and cultures all around the world for millennia, it is our belief that CBD, CBG, and the Hemp plant, will become more and more the leader in health & wellness, from its use in foods and protein supplements to its many benefits for the body and mind.
Read the whole paper:
https://www.nature.com/articles/s41598-024-66879-0
Initial Press Release: https://news.wsu.edu/press-release/2024/07/31/cannabinoid-cbg-reduces-anxiety-and-stress-in-first-human-clinical-trial/
Journal Reference:
Carrie Cuttler, Amanda Stueber, Ziva D. Cooper, Ethan Russo. Acute effects of cannabigerol on anxiety, stress, and mood: a double-blind, placebo-controlled, crossover, field trial. Scientific Reports, 2024; 14 (1) DOI: 10.1038/s41598-024-66879-0
